Skip to content

Senior Scientist - Analytical R&D - Antibody Drug Conjugates

Job Fair Calendar
Click HERE for a listing of on-site job fairs at member businesses throughout the region.

 

Employers
Members of the Nashoba Valley Chamber are provided the opportunity to post unlimited job openings at no fee. Click HERE to post your job or contact the Chamber office for assistance.

Non-members can post a job for a nominal fee. Contact the Chamber office for assistance.

 

Job Seekers

Sign up for job alerts

Click HERE to be added to our monthly email of current job postings.

Posted: 07/20/2025

We are seeking a highly motivated and skilled Senior Scientist with experience in analyzing antibody drug conjugates (ADC) to join our ARD team in New England. The successful candidate will play a hands-on role in the development, qualification, transfer, and validation of analytical methods to support the development of ADC’s and other complex bioconjugates. 

Core Responsibilities: 

  • Collaborate with cross-functional teams to drive impactful projects. 
  • Exercise technical judgment in the planning, implementation, and analysis of experiments related to method development, validation, reference standard creation and qualification, forced degradation, product characterization, and compatibility studies in accordance with pertinent ICH regulatory guidelines.
  • Perform method development, characterization, validation and analysis of bioconjugates including DAR (drug antibody ratio), DAR conjugation site occupancy, charge and size variants, purity, potency, free antibody and free linker payload using techniques such as HPLC, mass spectrometry, icIEF, SEC, CE-SDS, ELISA, Western Blot and UV-VIS spectrophotometry.
  • Author test methods, protocols, reports, and regulatory documents as needed.
  • Provide support for development and cGMP manufacturing campaigns, ensuring compliance with regulatory requirements and documentation standards - including both in-process and release samples.
  • Adhere to safety and quality standards. 
  • Communicate technical findings and results to both internal and external stakeholders, including clients and regulatory bodies.
  • Well organized with good problem-solving skills, a high level of attention to detail and have a passion for delivering high quality data in a fast-paced environment.
  • Collaborate with chemistry development scientists, quality control and regulatory affairs teams to ensure successful project delivery.
  • Mentor and develop scientific staff. Ensure continued technical and professional growth of department members, encourage efforts towards excellence and knowledge sharing.
  • Possess strong communication (oral, written), organizational, and leadership skills

Qualifications: 

Required

  • Ph.D., M.S., or B.S. in Analytical Chemistry, Biochemistry, Chemistry, Chemical/Biomedical Engineering, or other related scientific discipline.
  • Relevant experience in analytical method development, validation and characterization of bioconjugates. (PhD with 4+ years, MS with 8+ years, BS with 10 + years of experience)
  • Hands on experience with various techniques used in the characterization of ADC’s such as HPLC, mass spectrometry, icIEF, SEC, CE-SDS, Western Blot, UV-VIS spectrophotometry, etc.
  • Knowledge with cGMP, GLP, and regulatory guidelines for bioconjugate development.
  • Demonstrates good judgment, decision-making skills, and the ability to work both independently and in a team environment.
  • Skilled in technical writing.
  • Experience in mentoring staff in the analytical department.
  • Strong communication and teamwork skills in a cross-functional environment.

Scroll To Top